Why get gallium-67 or thallium-201 scans for bone tumors?
What percentage of osteogenic sarcoma patients have an elevated alkaline phosphatase?
True or false: preoperative systemic chemotherapy with methotrexate and other agents (including Adriamycin, BCD, cisplatin) have increased survival for osteogenic sarcoma from 15 percent up to more than 75 percent?
What is the overall disease-free survival for osteogenic sarcoma?
Does preoperative radiation therapy decrease the incidence of local tumor recurrence after resection of an osteogenic sarcoma?
If a bony tumor has grown out through the cortex into the soft tissue, can a biopsy of the soft tissue without violating the cortex provide an adequate diagnosis?
What percentage of patients with bony tumors require a second biopsy?
What is the incidence of skip metastases in bone tumors?
True or false: the synovial lining of the joint space usually acts as a barrier to tumor spread?
In limb salvage surgery, what is the distance from the edge of the bone reactivity on bone scan, up to which bone and adjacent muscles must be resected?
Intra-articular resection for osteogenic sarcoma has (bad or good) functional results?
True or false: an expandable endoprosthesis can help avoid limb length discrepancy with limb salvage techniques?
True or false: For femur midshaft tumors, reconstruction with allograft supported by an intramedullary prosthesis is quite effective?
What is the incidence of pathologic fracture after skeletal irradiation of bone tumors?
Osteogenic sarcoma: how many cases per year in United States?
What is the most common site of osteogenic sarcoma?
What disease causes the radiographic picture of an elevated periosteum with a sunburst appearance ?
Which is NOT a histologic form of osteogenic sarcoma?
Spindle cells are characteristic of Ewing's sarcoma or osteogenic sarcoma?
Most osteogenic sarcoma is aggressive or not; malignant-acting or not?
What type of children with osteogenic sarcoma have the worst prognosis?
Most common site of metastatic osteogenic sarcoma is what?
What drug is the best drug for reducing the incidence of lung metastases in osteogenic sarcoma?
What percentage of children with osteogenic sarcoma and lung metastases will also have bone metastases as well?
Vincristine given before methotrexate does what to the effects of methotrexate on the tumor cells?
What percentage of estrogenic sarcoma patients get limb salvage procedures?
T or F: When viable tumor cells are identified in a postoperative specimen, it means high risk for relapse from osteogenic sarcoma?
Multifocal osteogenic sarcoma probably represents osteogenic sarcoma that has metastasized to the bone directly without an intervening metastasis to what?
Paraosteal osteogenic sarcoma is (less or more) malignant form of osteogenic sarcoma; it arises on the outer surface of the bone and does not involve the medullary canal?
Where does Ewing's sarcoma develop from?
What is the histology of Ewing sarcoma?
What is the most common symptom of Ewing's sarcoma?
Which is NOT true regarding the differences between Ewing's sarcoma and a lymphoma involving bone?
What do onion skin changes on an x-ray suggest?
An MRI of the bone in Ewing's sarcoma shows what?
What histologic staining distinguishes Ewing sarcoma from metastatic rhabdomyosarcoma?
Where does Ewing's sarcoma mot frequently spread to?
True or false: CT scan of the chest should be obtained in newly diagnosed Ewing sarcoma?
Extraosseous Ewing's sarcoma spreads to the regional lymph nodes what percentage of the time?
Nodal metastases are (rare or common) in osseous Ewing sarcoma?
Radiation therapy is very helpful in treating Ewing sarcoma involving what?
True or false: surgical resection of Ewing sarcoma is almost always indicated, and amputation is often necessary?
True or false: preoperative chemotherapy and radiation therapy are often used to obtain limb salvage in Ewing's sarcoma?
What portion of the rib is removed when Ewing's occurs in the ribs?
True or false: Vertebral Ewing's has a very low recurrence rate?
What fraction of all chondrosarcomas occur in the pediatric age group?
Is the outcome for chondrosarcoma worse than or better than that for osteogenic sarcoma?
How is a lymphoma of the bone treated?
Where does the rare adamantinosarcoma occur?
What is the most common symptom of giant cell tumor of the bone in children?
What is the treatment of a LARGE giant cell tumor of the bone in children?
X-rays generally show a central sclerotic area with a lucent outer zone of reactive bone response; they are less than 1 cm in size often; patients may have focal night pain relieved by aspirin?
Local swelling and sometimes erythema are common, The treatment is local excision and curettage, and is 95 percent successful: Radiographically, the bone matrix is solid with radiolucent areas, bony reaction is mild?
Chicken wire calcification is seen. The most common symptom is focal pain. They are located in the femoral epiphysis or the epiphysis of the humerus, tibia, tarsal bones?
They are usually asymptomatic until a pathologic fracture develops. They are oval lesions in the metaphysis of the humerus, femur, tibia - longitudinally oriented, parallel to the bone. Radiographically they are lytic lesions?
They tend to be found after other bone lesions, either benign or malignant (for example chondroblastoma, giant cell tumor, osteogenic sarcoma, and others). For this reason, all of the aneurysmal bone cysts should be considered as having a possible underlying tumor. The symptoms are pain, swelling, tenderness, and heat?
Histologically they have increased fibroblasts and increased collagen; most are asymptomatic. The site affected is usually the lower extremity long bones, or the proximal humerus, ribs, skull. They are expansile lesions that erode the cortex and expand into the cancellous bone?
These are probably the end product of fibrous cortical dysplasia. The cortical margins are thin with dense endosteal response. They cause no pain?